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Fluconazole Coupon - Fluconazole 150mg tablet

fluconazole

Generic Diflucan
Used for Yeast Infection, Fungal Infection, Thrush
Used for Yeast Infection, Fungal Infection, Thrush

Fluconazole (Diflucan) is used to prevent and treat fungal infections. It's a recommended treatment option for vaginal yeast infections due to Candida and more severe cases of oral thrush (yeast infection in the mouth). Fluconazole (Diflucan) is generally well tolerated, but some people can experience side effects like headache, nausea, and stomach pain. This medication is available as a tablet, oral suspension, and injection that's given by a healthcare provider.

Last reviewed on April 19, 2023
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What is Fluconazole (Diflucan)?

What is Fluconazole (Diflucan) used for?

  • Vaginal yeast infection caused by Candida (tablets only)

  • Oral thrush of the mouth and throat caused by Candida

  • Bloodstream or systemic infection caused by Candida

  • Urinary tract infection (UTI) caused by Candida

  • Peritonitis (inflammation in the stomach lining) caused by Candida

  • Meningitis caused by Cryptococcus

  • Prevention of fungal infection caused by Candida for people having a bone marrow transplant

How Fluconazole (Diflucan) works

Fluconazole (Diflucan) is an antifungal. It slows the growth of the fungus that's causing your infection by damaging its protective layer.

Drug Facts

Common BrandsDiflucan
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Fluconazole (Diflucan) essentials

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What are the side effects of Fluconazole (Diflucan)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (13% for 150 mg single dose; 2% for all other doses)
  • Nausea (7% for 150 mg single dose; 4% for all other doses)
  • Stomach pain (6% for 150 mg single dose; 2% for all other doses)

Other Side Effects

  • Diarrhea
  • Vomiting
  • Upset stomach
  • Dizziness
  • Changes to taste
  • Skin rash

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Liver damage: nausea, vomiting, stomach pain, clay-colored stools, dark urine, yellowing of your skin or whites of your eyes
  • Severe allergic reaction: trouble breathing; hives; swelling of your face, tongue, or throat
  • Severe skin reactions: rash, blisters

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Chills

clay-colored stools

cough

dark urine

diarrhea

difficulty with swallowing

dizziness

fast heartbeat

fever

general feeling of tiredness or weakness

headache

hives, itching, or skin rash

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

light-colored stools

loss of appetite

nausea

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

stomach pain, continuing

tightness in the chest

unpleasant breath odor

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting

vomiting of blood

yellow eyes and skin

Incidence not known

Black, tarry stools

blistering, peeling, or loosening of the skin

chest pain or discomfort

decreased urine

dry mouth

fainting

hoarseness

increased thirst

irregular or slow heart rate

joint or muscle pain

loss of bladder control

lower back or side pain

mood changes

muscle pain or cramps

muscle spasm or jerking of the arms and legs

numbness or tingling in the hands, feet, or lips

painful or difficult urination

pale skin

red skin lesions, often with a purple center

red, irritated eyes

seizures

sore throat

sores, ulcers, or white spots in the mouth or on the lips

sudden loss of consciousness

swollen glands

unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Fearfulness, suspiciousness, or other mental changes

seeing, hearing, or feeling things that are not there

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Belching

change in taste or bad, unusual, or unpleasant (after) taste

heartburn

indigestion

stomach discomfort or upset

Incidence not known

Hair loss or thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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pros-and-cons

Pros and cons of Fluconazole (Diflucan)

thumbs-up

Pros

Works well to treat many types of fungal infections

Typically only need one dose for vaginal yeast infections

Available as a tablet, oral liquid, or injection

Oral liquid comes flavored for better taste

Available as a lower-cost generic

thumbs-down

Cons

Requires a prescription

Might cause liver damage

Interacts with many medications, like certain cholesterol medications

Might cause harm to unborn babies if taken during pregnancy

Single oral dose for vaginal yeast infections has more side effects than products that are directly applied to the area

pharmacist-tips

Pharmacist tips for Fluconazole (Diflucan)

pharmacist
  • You can take fluconazole (Diflucan) with or without food. If you experience nausea or upset stomach after taking this medication, try taking fluconazole (Diflucan) with food to help lessen these side effects.

    • Finish all of the fluconazole (Diflucan) your healthcare provider prescribed for you, even if you start to feel better. Stopping fluconazole (Diflucan) too soon can cause your infection to come back.

      • If you're using fluconazole (Diflucan) to treat a vaginal yeast infection, avoid having sex until your infection is completely better. Having sex before your infection is cleared up can be painful and make symptoms, like burning and itching, worse. There's also a risk to pass the infection to your partner.

        • Fluconazole (Diflucan) can interact with several medications, such as warfarin (Coumadin), atorvastatin (Lipitor), erythromycin, and some diabetes medications. This isn't a complete list of everything that interferes with fluconazole (Diflucan). So, be sure to tell your pharmacist about all the medications you take, including things available over the counter, vitamins, and herbal supplements.

          Additional tips for the oral suspension

          • Shake the fluconazole (Diflucan) oral suspension each time before you measure out and take your dose.

            • Only use the measuring device provided at the pharmacy. Don't use household spoons to measure your dose since this could cause you to take the wrong amount.

              • Store fluconazole (Diflucan) at room temperature. Throw the medication away after 2 weeks, even if there's still some left over.

                More on Fluconazole (Diflucan) tips

                faqs

                Frequently asked questions about Fluconazole (Diflucan)

                How long does it take for fluconazole (Diflucan) to work?
                It depends on the type of infection you're treating and how severe it was before you started taking fluconazole (Diflucan). For a vaginal yeast infection, symptoms should improve within a couple days after you take your dose. If they don't start to get better within 3 days, call your provider. If you're taking fluconazole (Diflucan) for oral thrush, your symptoms should get better within several days. Continue taking fluconazole (Diflucan) for the amount of time your provider recommended, even if your symptoms improve and you're feeling better. Stopping treatment too early can cause your infection to come back or be harder to treat.
                How often can you take fluconazole (Diflucan) for a vaginal yeast infection?
                You'll typically take fluconazole (Diflucan) once as a single dose each time you get a vaginal yeast infection. But, if you have 3 or more vaginal yeast infections in under a year, your healthcare provider will want to examine you to see if your yeast infections need to be treated differently.
                How long do fluconazole (Diflucan) side effects last?
                Most side effects of fluconazole (Diflucan) are mild. It isn't exactly known how long side effects last when you're taking fluconazole (Diflucan). But side effects should generally go away within a few days after you stop taking it. If you still have side effects after a week of stopping fluconazole (Diflucan), contact your healthcare provider. They can check to make sure nothing else is going on.
                Can I buy fluconazole (Diflucan) over the counter?
                No. In the United States, fluconazole (Diflucan) is available by prescription only. There are other options to treat vaginal yeast infections that you can buy over the counter. But, if it's your first potential yeast infection or if you aren't sure if it is one, it's recommended to see your healthcare provider before starting any treatments. They can help you make sure you're treating your infection properly.
                Can you drink while taking fluconazole (Diflucan)?
                Talk to your provider about whether it's safe to drink alcohol while you're taking fluconazole (Diflucan). In general, it's best to avoid alcohol until you're done taking fluconazole (Diflucan) since alcohol can potentially weaken your immune system. This might make it harder for you to get better. Additionally, drinking alcohol might raise your risk of or worsen some side effects, like nausea, stomach pain, and diarrhea. Something else to keep in mind is that both alcohol and fluconazole (Diflucan) could potentially cause liver damage.
                Does fluconazole (Diflucan) treat BV?
                No, fluconazole (Diflucan) can't treat bacterial vaginosis (BV). BV is caused by an imbalance of good and bad bacteria in the vagina. It's treated with antibiotics like metronidazole (Flagyl). Fluconazole (Diflucan) is an antifungal, so it treats infections caused by fungi instead of bacteria. For this reason, fluconazole (Diflucan) won't work to treat BV. Symptoms of a vaginal yeast infection and BV can be similar. Your healthcare provider can make sure you get the appropriate treatment for your infection.
                Can you take fluconazole (Diflucan) while pregnant?
                Fluconazole (Diflucan) generally isn't recommended for pregnant women. Studies suggest that fluconazole (Diflucan) can harm unborn babies when taken during the first trimester. The risk is higher if you're taking high doses of fluconazole (Diflucan) for a long period of time. According to the FDA, a single 150 mg dose to treat vaginal yeast infections during pregnancy doesn't appear to be linked to birth defects. But the CDC doesn't recommend it because of the potential risk. If you're pregnant or think you might be pregnant, talk to your healthcare provider before taking fluconazole (Diflucan). If you're taking 400 mg to 800 mg of fluconazole (Diflucan) per day, it's recommended to use effective birth control during treatment and for 1 week after your last dose.
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                warings-icon

                What are the risks and warnings for Fluconazole (Diflucan)?

                Fluconazole (Diflucan) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Liver damage

                • Risk factors: Liver problems | Excessive alcohol use

                  Rarely, people taking fluconazole (Diflucan) have experienced serious liver damage. Most of the time, the damage completely heals once you stop taking fluconazole (Diflucan). Your risk of liver damage might be higher if you already have liver problems. Drinking a lot of alcohol while taking this medication can also raise your risk of liver damage. If you notice yellowing of the whites of your eyes or skin, dark urine, or stomach pain, talk to your healthcare provider. They'll probably order blood tests to check your liver health.

                  risk-warning

                  Allergic reaction

                  Allergic reactions to fluconazole (Diflucan) are possible, including life-threatening problems like anaphylaxis (closing of the throat). Call 911 if this happens. If you notice hives, a rash, swelling of the lips or tongue, or difficulty breathing after taking fluconazole (Diflucan), call your healthcare provider right away.

                  risk-warning

                  Severe skin reaction

                  Very rarely, people have developed a serious, potentially life-threatening skin reaction called exfoliative dermatitis after starting fluconazole (Diflucan). This serious rash can cause itchiness, redness all over your body, and scaly and peeling skin. Get medical help right away if you notice a new or severe rash with fever, skin redness, or unexplained blisters.

                  risk-warning

                  Harm to unborn babies

                  Fluconazole (Diflucan) hasn't been studied very much in pregnant women. Available studies suggest that there might be a risk of birth defects or a miscarriage if fluconazole (Diflucan) is taken during the first trimester. But more research is needed to learn more about how safe this medication is to take during pregnancy. If you're taking 400 mg to 800 mg of fluconazole (Diflucan) per day, it's recommended to use birth control during treatment and for 1 week after your last dose. If you become pregnant while you're taking fluconazole (Diflucan), stop taking the medication right away and talk to your healthcare provider.

                  dosage

                  Fluconazole (Diflucan) dosage forms

                  bottle of oral suspension
                  Bottle of oral suspension
                  DosageAs low as
                  35ml of 10mg/ml$10.40 for 1 bottle
                  35ml of 40mg/ml$27.59 for 1 bottle
                  tablet
                  Tablet
                  DosageAs low as
                  50mg$22.00 for 60 tablets
                  100mg$2.99 for 7 tablets
                  150mg$6.00 for 2 tablets
                  200mg$30.00 for 60 tablets

                  Typical dosing for Fluconazole (Diflucan)

                  Adults:

                  • Vaginal yeast infection: The typical dose is 150 mg by mouth taken one time only.

                  • Oral thrush: The typical dose is 200 mg by mouth on the first day, followed by 100 mg once daily.

                  • Bloodstream or systemic infection: Your dose will depend on how your infection responds to fluconazole (Diflucan). Doses of up to 400 mg by mouth per day can be given.

                  • UTI and peritonitis: The typical dose is 50 mg to 200 mg by mouth once daily.

                  • Cryptococcal meningitis: The typical dose is 400 mg by mouth on the first day, followed by 200 mg once daily. Most people with this condition will take fluconazole (Diflucan) for several months. Some people might need to take it long term to prevent the infection from coming back.

                  • Prevention of fungal infection: The typical dose is 400 mg by mouth once daily, usually starting several days before the bone marrow transplant takes place.

                  Children: Your child's provider will calculate their dose based on their body weight.

                  Your dose might differ if you have kidney problems.

                  Fluconazole (Diflucan) is also available as an intravenous (IV) injection that's given by a healthcare provider.

                  More on Fluconazole (Diflucan) dosage forms

                  interactions

                  Interactions between Fluconazole (Diflucan) and other drugs

                  Fluconazole (Diflucan) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Fluconazole (Diflucan). Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                  Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                  contraindications-icon

                  Fluconazole (Diflucan) contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Fluconazole (Diflucan) will not be safe for you to take.
                  alternatives

                  What are alternatives to Fluconazole (Diflucan)?

                  There are a number of medications that your doctor can prescribe in place of Fluconazole (Diflucan). Compare a few possible alternatives below.
                  Fluconazole (Diflucan)
                  Used for:
                  • Vaginal yeast infection caused by Candida (tablets only)

                  • Oral thrush of the mouth and throat caused by Candida

                  • Bloodstream or systemic infection caused by Candida

                  • Urinary tract infection (UTI) caused by Candida

                  • Peritonitis (inflammation in the stomach lining) caused by Candida

                  • Meningitis caused by Cryptococcus

                  • Prevention of fungal infection caused by Candida for people having a bone marrow transplant

                  $6.00 Lowest GoodRx priceView Prices
                  Used for:
                  • Treatment of vaginal yeast infection

                  • Relief of vaginal yeast infection symptoms (itching and irritation outside of the vagina)

                  $6.07 Lowest GoodRx priceView Prices
                  Used for:
                  • Oral thrush of the mouth and throat (liquid only)

                  • Fungal infections of the stomach and intestines (tablet only)

                  $11.00 Lowest GoodRx priceView Prices
                  latest news

                  What is the latest news about Fluconazole (Diflucan)?

                  images

                  Fluconazole (Diflucan) images

                  Pink Oblong C And 10 - Fluconazole 150mg Tablet
                  This medicine is Pink, Oblong Tablet Imprinted With "C" And "10".Pink Oblong C And 10 - Fluconazole 150mg Tablet
                  Pink Oval Flz 150 - Fluconazole 150mg Tablet
                  This medicine is Pink, Oval Tablet Imprinted With "Flz 150".Pink Oval Flz 150 - Fluconazole 150mg Tablet
                  Pink Round H 603 - Fluconazole 150mg Tablet
                  This medicine is Pink, Round Tablet Imprinted With "H 603".Pink Round H 603 - Fluconazole 150mg Tablet
                  Pink Oval 1139 - Fluconazole 150mg Tablet
                  This medicine is Pink, Oval Tablet Imprinted With "1139".Pink Oval 1139 - Fluconazole 150mg Tablet

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                  References

                  Best studies we found

                  Aurobindo Pharma Limited. (2023). Fluconazole [package insert]. DailyMed.

                  Austad, S. S., et al. (2022). Exfoliative dermatitis. StatPearls.

                  Centers for Disease Control and Prevention. (2021). Candida infections of the mouth, throat, and esophagus.

                  View All References (15)

                  Centers for Disease Control and Prevention. (2021). Sexually transmitted infections treatment guidelines, 2021: Bacterial vaginosis.

                  Centers for Disease Control and Prevention. (2021). Vulvovaginal candidiasis.

                  Centers for Disease Control and Prevention. (2022). Antimicrobial-resistant fungi.

                  Centers for Disease Control and Prevention. (2022). Bacterial vaginosis (BV): Fact sheet.

                  Heritage Pharmaceuticals. (2022). Nystatin tablet [package insert]. DailyMed.

                  Hikma Pharmaceuticals USA. (2021). Fluconazole [package insert]. DailyMed.

                  InformedHealth.org. (2022). Vaginal yeast infection (thrush): Overview. Institute for Quality and Efficiency in Health Care.

                  LiverTox: Clinical Research Information on Drug-Induced Liver Injury. (2017). Fluconazole. National Institute of Diabetes and Digestive and Kidney Diseases.

                  MedlinePlus. (2022). Bone marrow transplant.

                  MedlinePlus. (2022). Bone marrow transplant.

                  Nivagen Pharmaceuticals. (2022). Nystatin suspension [package insert]. DailyMed.

                  Office of the Assistant Secretary of Health. (2021). Vaginal yeast infections.

                  Pappas, P. G., et al. (2015). Clinical practice guidelines for the management of candidiases: 2016 update by the Infectious Diseases Society of America. Clinical Infectious Diseases.

                  Roerig. (2023). Diflucan [package insert]. DailyMed.

                  U.S. Food and Drug Administration. (2017). FDA drug safety communication: Use of long-term, high-dose Diflucan (fluconazole) during pregnancy may be associated with birth defects in infants.

                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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